Yersinia effector protein (YopO)-mediated phosphorylation of host gelsolin causes calcium-independent activation leading to disruption of actin dynamics.

Yersinia effector protein (YopO)-mediated phosphorylation of host gelsolin causes calcium-independent activation leading to disruption of actin dynamics.

Pathogenic Yersinia bacteria cause a range of human diseases. To modulate and evade host immune systems, these yersiniae inject effector proteins into host macrophages. One such protein, the serine/threonine kinase YopO (YpkA in Yersinia pestis), uses monomeric actin as bait to recruit and phosphory...

書誌詳細
主要な著者:	Singaravelu, P, Lee, W, Wee, S, Ghoshdastider, U, Ding, K, Gunaratne, J, Grimes, J, Swaminathan, K, Robinson, R
フォーマット:	Journal article
言語:	English
出版事項:	American Society for Biochemistry and Molecular Biology 2017

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