Uncoupling VEGFA Functions in Arteriogenesis and Hematopoietic Stem Cell Specification

VEGFA signaling is critical for endothelial and hematopoietic stem cell (HSC) specification. However, blood defects resulting from perturbation of the VEGFA pathway are always accompanied by impaired vascular/arterial development. Because HSCs derive from arterial cells, it is unclear whether VEGFA...

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Bibliographic Details
Main Authors: Leung, A, Ciau-Uitz, A, Pinheiro, P, Monteiro, R, Zuo, J, Vyas, P, Patient, R, Porcher, C
Format: Journal article
Language:English
Published: 2013