The role of DNA-demethylating agents in cancer therapy

DNA methylation patterns are frequently altered in cancer cells as compared to normal cells. A large body of research associates these DNA methylation aberrations with cancer initiation and progression. Moreover, cancer cells seem to depend upon these aberrant DNA methylation profiles to thrive. Fin...

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Hlavní autoři: Mehdipour, P, Murphy, T, De Carvalho, DD
Médium: Journal article
Jazyk:English
Vydáno: Elsevier 2019