Residual embryonic cells as precursors of a Barrett's-like metaplasia.
Barrett's esophagus is an intestine-like metaplasia and precursor of esophageal adenocarcinoma. Triggered by gastroesophageal reflux disease, the origin of this metaplasia remains unknown. p63-deficient mice, which lack squamous epithelia, may model acid-reflux damage. We show here that p63 nul...
Main Authors: | Wang, X, Ouyang, H, Yamamoto, Y, Kumar, P, Wei, T, Dagher, R, Vincent, M, Lu, X, Bellizzi, A, Ho, K, Crum, C, Xian, W, McKeon, F |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
2011
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