Photocatalytic three-component umpolung synthesis of 1,3-diamines

A visible-light-mediated photocatalytic umpolung synthesis of 1,3-diamines from in situ-generated imines and dehydroalanine derivatives is described. Pivoting on a key nucleophilic addition of photocatalytically generated α-amino radicals to electron-deficient alkenes, this three-component coupling...

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Hlavní autoři: Rossolini, T, Leitch, J, Grainger, R, Dixon, D
Médium: Journal article
Jazyk:English
Vydáno: American Chemical Society 2018