Glycosidase-inhibiting pyrrolidine alkaloids from Hyacinthoides non-scripta
The glycosidase-inhibiting pyrrolidine alkaloids (2R,3R,4R,5R)-2,5- dihydroxymethyl-3,4-dihydroxy-pyrrolidine (DMDP), 2,5-dideoxy-2,5-imino-DL- glycero-D-manno-heptitol (homoDMDP), homoDMDP-7-O-apioside and 1,4-dideoxy- 1,4-imino-D-arabinitol have been identified in the leaves of bluebells (Hyacinth...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
1997
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| _version_ | 1797100411521335296 |
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| author | Watson, A Nash, R Wormald, MR Harvey, D Dealler, S Lees, E Asano, N Kizu, H Kato, A Griffiths, R Cairns, A Fleet, G |
| author_facet | Watson, A Nash, R Wormald, MR Harvey, D Dealler, S Lees, E Asano, N Kizu, H Kato, A Griffiths, R Cairns, A Fleet, G |
| author_sort | Watson, A |
| collection | OXFORD |
| description | The glycosidase-inhibiting pyrrolidine alkaloids (2R,3R,4R,5R)-2,5- dihydroxymethyl-3,4-dihydroxy-pyrrolidine (DMDP), 2,5-dideoxy-2,5-imino-DL- glycero-D-manno-heptitol (homoDMDP), homoDMDP-7-O-apioside and 1,4-dideoxy- 1,4-imino-D-arabinitol have been identified in the leaves of bluebells (Hyacinthoides non-scripta). HomoDMDP and homoDMDP-7-O-apioside are new natural products. Glycosidase inhibition by the aglycones is compared and could explain the symptoms of poisoning of livestock by bluebells. |
| first_indexed | 2024-03-07T05:37:06Z |
| format | Journal article |
| id | oxford-uuid:e448e06f-748c-4ddd-828e-459de63051cb |
| institution | University of Oxford |
| last_indexed | 2024-03-07T05:37:06Z |
| publishDate | 1997 |
| record_format | dspace |
| spelling | oxford-uuid:e448e06f-748c-4ddd-828e-459de63051cb2022-03-27T10:15:27ZGlycosidase-inhibiting pyrrolidine alkaloids from Hyacinthoides non-scriptaJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e448e06f-748c-4ddd-828e-459de63051cbSymplectic Elements at Oxford1997Watson, ANash, RWormald, MRHarvey, DDealler, SLees, EAsano, NKizu, HKato, AGriffiths, RCairns, AFleet, GThe glycosidase-inhibiting pyrrolidine alkaloids (2R,3R,4R,5R)-2,5- dihydroxymethyl-3,4-dihydroxy-pyrrolidine (DMDP), 2,5-dideoxy-2,5-imino-DL- glycero-D-manno-heptitol (homoDMDP), homoDMDP-7-O-apioside and 1,4-dideoxy- 1,4-imino-D-arabinitol have been identified in the leaves of bluebells (Hyacinthoides non-scripta). HomoDMDP and homoDMDP-7-O-apioside are new natural products. Glycosidase inhibition by the aglycones is compared and could explain the symptoms of poisoning of livestock by bluebells. |
| spellingShingle | Watson, A Nash, R Wormald, MR Harvey, D Dealler, S Lees, E Asano, N Kizu, H Kato, A Griffiths, R Cairns, A Fleet, G Glycosidase-inhibiting pyrrolidine alkaloids from Hyacinthoides non-scripta |
| title | Glycosidase-inhibiting pyrrolidine alkaloids from Hyacinthoides non-scripta |
| title_full | Glycosidase-inhibiting pyrrolidine alkaloids from Hyacinthoides non-scripta |
| title_fullStr | Glycosidase-inhibiting pyrrolidine alkaloids from Hyacinthoides non-scripta |
| title_full_unstemmed | Glycosidase-inhibiting pyrrolidine alkaloids from Hyacinthoides non-scripta |
| title_short | Glycosidase-inhibiting pyrrolidine alkaloids from Hyacinthoides non-scripta |
| title_sort | glycosidase inhibiting pyrrolidine alkaloids from hyacinthoides non scripta |
| work_keys_str_mv | AT watsona glycosidaseinhibitingpyrrolidinealkaloidsfromhyacinthoidesnonscripta AT nashr glycosidaseinhibitingpyrrolidinealkaloidsfromhyacinthoidesnonscripta AT wormaldmr glycosidaseinhibitingpyrrolidinealkaloidsfromhyacinthoidesnonscripta AT harveyd glycosidaseinhibitingpyrrolidinealkaloidsfromhyacinthoidesnonscripta AT deallers glycosidaseinhibitingpyrrolidinealkaloidsfromhyacinthoidesnonscripta AT leese glycosidaseinhibitingpyrrolidinealkaloidsfromhyacinthoidesnonscripta AT asanon glycosidaseinhibitingpyrrolidinealkaloidsfromhyacinthoidesnonscripta AT kizuh glycosidaseinhibitingpyrrolidinealkaloidsfromhyacinthoidesnonscripta AT katoa glycosidaseinhibitingpyrrolidinealkaloidsfromhyacinthoidesnonscripta AT griffithsr glycosidaseinhibitingpyrrolidinealkaloidsfromhyacinthoidesnonscripta AT cairnsa glycosidaseinhibitingpyrrolidinealkaloidsfromhyacinthoidesnonscripta AT fleetg glycosidaseinhibitingpyrrolidinealkaloidsfromhyacinthoidesnonscripta |