The functional organization of mitochondrial genomes in human cells

Background: We analyzed the organization and function of mitochondrial DNA in a stable human cell line (ECV304, which is also known as T-24) containing mitochondria tagged with the yellow fluorescent protein. Results: Mitochondrial DNA is organized in ~475 discrete foci containing 6–10 genomes. Thes...

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Bibliographic Details
Main Authors: Iborra, F, Kimura, H, Cook, P
Format: Journal article
Language:English
Published: BioMed Central 2004
Subjects: