CBP/p300 as a co-factor for the Microphthalmia transcription factor.

The Microphthalmia basic-Helix-Loop-Helix-Leucine Zipper (bHLH-LZ) transcription factor (Mi) plays a crucial role in the genesis of melanocytes; mice deficient for a functional (Microphthalmia) gene product lack all pigment cells. We show here that the Mi activation domain resides N-terminal to the...

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Autors principals: Sato, S, Roberts, K, Gambino, G, Cook, A, Kouzarides, T, Goding, C
Format: Journal article
Idioma:English
Publicat: 1997