ASPP2 suppresses squamous cell carcinoma via RelA/p65-mediated repression of p63.

ASPP2 suppresses squamous cell carcinoma via RelA/p65-mediated repression of p63.

Squamous cell carcinoma (SCC) is highly malignant and refractory to therapy. The majority of existing mouse SCC models involve multiple gene mutations. Very few mouse models of spontaneous SCC have been generated by a single gene deletion. Here we report a haploinsufficient SCC mouse model in which...

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Bibliographic Details
Main Authors: Tordella, L, Koch, S, Salter, V, Pagotto, A, Doondeea, J, Feller, S, Ratnayaka, I, Zhong, S, Goldin, R, Lozano, G, McKeon, F, Tavassoli, M, Fritzsche, F, Huber, G, Rössle, M, Moch, H, Lu, X
Format: Journal article
Language:English
Published: 2013

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