Aortic thrombosis in COVID-19
Background Venous thrombo-embolism is now well-recognised as a common complication of severe COVID-19 disease. Arterial thrombosis has been less well recognised, although it is increasingly reported, mostly in the context of myocardial infarction and stroke. Case report A 63-year-old man developed...
| Main Authors: | , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Elsevier
2020
|
| _version_ | 1797100435298844672 |
|---|---|
| author | Wickham, H Tam, JCH Chan, XHS George, MJ Levi, M Brown, M |
| author_facet | Wickham, H Tam, JCH Chan, XHS George, MJ Levi, M Brown, M |
| author_sort | Wickham, H |
| collection | OXFORD |
| description | Background
Venous thrombo-embolism is now well-recognised as a common complication of severe COVID-19 disease. Arterial thrombosis has been less well recognised, although it is increasingly reported, mostly in the context of myocardial infarction and stroke.
Case report
A 63-year-old man developed a pale, cold foot with an absent dorsalis pedis pulse 7 days into his admission with COVID-19. A CT angiogram demonstrated a large thrombus in the lower thoracic aorta, which had not been present on CT pulmonary angiogram the preceding week, along with occlusion of both popliteal arteries. He was managed with therapeutic dose of low molecular weight heparin (LMWH) for 6 weeks.
Results
This case adds to the growing list of potential sites and consequences of thrombosis in COVID-19.
Conclusion
This case underscores the urgent need for pathophysiological studies and clinical trials to target treatments and guidelines for thromboprophylaxis in COVID-19.
|
| first_indexed | 2024-03-07T05:37:27Z |
| format | Journal article |
| id | oxford-uuid:e467a43d-af45-45a5-aa5d-29f98a6d9597 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:37:27Z |
| publishDate | 2020 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:e467a43d-af45-45a5-aa5d-29f98a6d95972022-03-27T10:16:22ZAortic thrombosis in COVID-19Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e467a43d-af45-45a5-aa5d-29f98a6d9597EnglishSymplectic ElementsElsevier2020Wickham, HTam, JCHChan, XHSGeorge, MJLevi, MBrown, MBackground Venous thrombo-embolism is now well-recognised as a common complication of severe COVID-19 disease. Arterial thrombosis has been less well recognised, although it is increasingly reported, mostly in the context of myocardial infarction and stroke. Case report A 63-year-old man developed a pale, cold foot with an absent dorsalis pedis pulse 7 days into his admission with COVID-19. A CT angiogram demonstrated a large thrombus in the lower thoracic aorta, which had not been present on CT pulmonary angiogram the preceding week, along with occlusion of both popliteal arteries. He was managed with therapeutic dose of low molecular weight heparin (LMWH) for 6 weeks. Results This case adds to the growing list of potential sites and consequences of thrombosis in COVID-19. Conclusion This case underscores the urgent need for pathophysiological studies and clinical trials to target treatments and guidelines for thromboprophylaxis in COVID-19. |
| spellingShingle | Wickham, H Tam, JCH Chan, XHS George, MJ Levi, M Brown, M Aortic thrombosis in COVID-19 |
| title | Aortic thrombosis in COVID-19 |
| title_full | Aortic thrombosis in COVID-19 |
| title_fullStr | Aortic thrombosis in COVID-19 |
| title_full_unstemmed | Aortic thrombosis in COVID-19 |
| title_short | Aortic thrombosis in COVID-19 |
| title_sort | aortic thrombosis in covid 19 |
| work_keys_str_mv | AT wickhamh aorticthrombosisincovid19 AT tamjch aorticthrombosisincovid19 AT chanxhs aorticthrombosisincovid19 AT georgemj aorticthrombosisincovid19 AT levim aorticthrombosisincovid19 AT brownm aorticthrombosisincovid19 |