Substrate conformational dynamics facilitate structure-specific recognition of gapped DNA by DNA polymerase
DNA-binding proteins utilise different recognition mechanisms to locate their DNA targets; some proteins recognise specific DNA sequences, while others interact with specific DNA structures. While sequence-specific DNA binding has been studied extensively, structure-specific recognition mechanisms r...
Main Authors: | Craggs, T, Sustarsic, M, Plochowietz, A, Mosayebi, M, Kaju, H, Cuthbert, A, Hohlbein, J, Domicevica, L, Biggin, P, Doye, J, Kapanidis, A |
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Format: | Journal article |
Language: | English |
Published: |
Oxford University Press
2019
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