Substrate conformational dynamics facilitate structure-specific recognition of gapped DNA by DNA polymerase

Substrate conformational dynamics facilitate structure-specific recognition of gapped DNA by DNA polymerase

DNA-binding proteins utilise different recognition mechanisms to locate their DNA targets; some proteins recognise specific DNA sequences, while others interact with specific DNA structures. While sequence-specific DNA binding has been studied extensively, structure-specific recognition mechanisms r...

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Detalles Bibliográficos
Main Authors: Craggs, T, Sustarsic, M, Plochowietz, A, Mosayebi, M, Kaju, H, Cuthbert, A, Hohlbein, J, Domicevica, L, Biggin, P, Doye, J, Kapanidis, A
Formato: Journal article
Idioma:English
Publicado: Oxford University Press 2019

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