Substrate conformational dynamics facilitate structure-specific recognition of gapped DNA by DNA polymerase

Substrate conformational dynamics facilitate structure-specific recognition of gapped DNA by DNA polymerase

DNA-binding proteins utilise different recognition mechanisms to locate their DNA targets; some proteins recognise specific DNA sequences, while others interact with specific DNA structures. While sequence-specific DNA binding has been studied extensively, structure-specific recognition mechanisms r...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Craggs, T, Sustarsic, M, Plochowietz, A, Mosayebi, M, Kaju, H, Cuthbert, A, Hohlbein, J, Domicevica, L, Biggin, P, Doye, J, Kapanidis, A
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	Oxford University Press 2019

समान संसाधन

DNA polymerase conformational dynamics and the role of fidelity-conferring residues: Insights from computational simulations
द्वारा: Meli, M, और अन्य
प्रकाशित: (2016)

The rate-limiting step of DNA synthesis by DNA polymerase occurs in the fingers-closed conformation
द्वारा: Evans, GW, और अन्य
प्रकाशित: (2021)

Conformational landscapes of DNA polymerase I and mutator derivatives establish fidelity checkpoints for nucleotide insertion.
द्वारा: Hohlbein, J, और अन्य
प्रकाशित: (2013)

Conformational transitions in DNA polymerase I revealed by single-molecule FRET.
द्वारा: Santoso, Y, और अन्य
प्रकाशित: (2010)

Optimized Internalization of Fluorescently Labeled Biomolecules into Live Bacteria
द्वारा: Sustarsic, M, और अन्य
प्रकाशित: (2014)

In vitro, in silico and in vivo studies of the structure and conformational dynamics of DNA Polymerase I
द्वारा: Sustarsic, M
प्रकाशित: (2015)

RNA polymerase clamp conformational dynamics: long-lived states and modulation by crowding, cations, and nonspecific DNA binding
द्वारा: Mazumder, A, और अन्य
प्रकाशित: (2021)

Stable end-sealed DNA as robust nano-rulers for in vivo single-molecule fluorescence
द्वारा: Plochowietz, A, और अन्य
प्रकाशित: (2016)

DNA Polymerase: Structural Homology, Conformational Dynamics, and the Effects of Carcinogenic DNA Adducts
द्वारा: Richard G. Federley, और अन्य
प्रकाशित: (2010-01-01)

Single-Molecule Fluorescence and FRET Measurements on Internalized Proteins in Living Bacteria
द्वारा: Aigrain, L, और अन्य
प्रकाशित: (2013)

Phosphorylation Induced Conformational Transitions in DNA Polymerase β
द्वारा: Amit Srivastava, और अन्य
प्रकाशित: (2022-06-01)

Therminator DNA Polymerase: Modified Nucleotides and Unnatural Substrates
द्वारा: Andrew F. Gardner, और अन्य
प्रकाशित: (2019-04-01)

Optimized delivery of fluorescently labeled proteins in live bacteria using electroporation.
द्वारा: Sustarsic, M, और अन्य
प्रकाशित: (2014)

The role of loop stacking in the dynamics of DNA hairpin formation.
द्वारा: Mosayebi, M, और अन्य
प्रकाशित: (2014)

Real-time transcription initiation by E. coli RNA polymerase in vitro and in vivo
द्वारा: Plochowietz, A, और अन्य
प्रकाशित: (2015)

Global conformational dynamics of a Y-family DNA polymerase during catalysis.
द्वारा: Cuiling Xu, और अन्य
प्रकाशित: (2009-10-01)

Comparative analysis of T4 DNA ligases and DNA polymerases used in chromosome conformation capture assays
द्वारा: Michal Schwartz, और अन्य
प्रकाशित: (2015-04-01)

Initial transcription by RNA polymerase proceeds through a DNA-scrunching mechanism.
द्वारा: Kapanidis, A, और अन्य
प्रकाशित: (2006)

Real-time single-molecule observations of conformational changes in DNA polymerase
द्वारा: Evans, GW
प्रकाशित: (2013)

DNA polymerase α-primase facilitates PARP inhibitor-induced fork acceleration and protects BRCA1-deficient cells against ssDNA gaps
द्वारा: Zuzana Machacova, और अन्य
प्रकाशित: (2024-08-01)

The transcription bubble of the RNA polymerase-promoter open complex exhibits conformational heterogeneity and millisecond-scale dynamics: Implications for transcription start-site selection
द्वारा: Robb, N, और अन्य
प्रकाशित: (2013)

The transcription bubble of the RNA polymerase-promoter open complex exhibits conformational heterogeneity and millisecond-scale dynamics: implications for transcription start-site selection.
द्वारा: Robb, N, और अन्य
प्रकाशित: (2013)

Tethered fluorophore motion: studying large DNA conformational changes by single-fluorophore imaging.
द्वारा: May, P, और अन्य
प्रकाशित: (2014)

The combined DNA and RNA synthetic capabilities of archaeal DNA primase facilitate primer hand-off to the replicative DNA polymerase
द्वारा: Mark D. Greci, और अन्य
प्रकाशित: (2022-01-01)

Bacterial DNA, DNA polymerase, and DNA helicases /
द्वारा: Knudsen, Walter D., और अन्य
प्रकाशित: (c201)

Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy
द्वारा: Kouta Mayanagi, और अन्य
प्रकाशित: (2020-10-01)

A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA
द्वारा: Xingchen Liu, और अन्य
प्रकाशित: (2022-06-01)

A Unique B-Family DNA Polymerase Facilitating Error-Prone DNA Damage Tolerance in Crenarchaeota
द्वारा: Xu Feng, और अन्य
प्रकाशित: (2020-07-01)

Dynamic conformational change regulates the protein-DNA recognition: an investigation on binding of a Y-family polymerase to its target DNA.
द्वारा: Xiakun Chu, और अन्य
प्रकाशित: (2014-09-01)

Input files for example oxDNA simulations of DNA origami
द्वारा: Doye, J
प्रकाशित: (2020)

DNA nanotweezers studied with a coarse-grained model of DNA.
द्वारा: Ouldridge, T, और अन्य
प्रकाशित: (2010)

DNA nanotweezers studied with a coarse-grained model of DNA
द्वारा: Ouldridge, T, और अन्य
प्रकाशित: (2010)

Force-induced rupture of a DNA duplex: from fundamentals to force sensors
द्वारा: Mosayebi, M, और अन्य
प्रकाशित: (2015)

DNA Polymerase Gamma in Mitochondrial DNA Replication and Repair
द्वारा: William C. Copeland, और अन्य
प्रकाशित: (2003-01-01)

Conformational Selection and Induced Fit for RNA Polymerase and RNA/DNA Hybrid Backtracked Recognition
द्वारा: Haifeng eChen, और अन्य
प्रकाशित: (2015-11-01)

Homology modelling of human P-glycoprotein.
द्वारा: Domicevica, L, और अन्य
प्रकाशित: (2015)

Translocation of sigma(70) with RNA polymerase during transcription: fluorescence resonance energy transfer assay for movement relative to DNA.
द्वारा: Mukhopadhyay, J, और अन्य
प्रकाशित: (2001)

Molecular basis for DNA repair synthesis on short gaps by mycobacterial Primase-Polymerase C
द्वारा: Nigel C. Brissett, और अन्य
प्रकाशित: (2020-08-01)

DNA polymerases and diseases
द्वारा: Ramadan, K, और अन्य
प्रकाशित: (2007)

Isothermal Amplification and Multimerization of DNA by Bst DNA Polymerase
द्वारा: G.J. Hafner, और अन्य
प्रकाशित: (2001-04-01)