HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O(2) levels.

HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O(2) levels.

Hypoxia-inducible factor (HIF) is a heterodimeric transcription factor that plays a crucial role in mediating cellular responses to oxygen. Oxygen availability influences multiple steps in HIF activation and recent studies have indicated that at least two steps in this process are governed by a nove...

Detaylı Bibliyografya
Asıl Yazarlar:	Masson, N, Ratcliffe, P
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2003

Benzer Materyaller

Tuning the transcriptional response to hypoxia by inhibiting HIF prolyl- and asparaginyl-hydroxylases
Yazar:: Chan, M, ve diğerleri
Baskı/Yayın Bilgisi: (2016)

Regulation of HIF: prolyl hydroxylases.
Yazar:: Stolze, I, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

2-oxoglutarate analogue inhibitors of HIF prolyl hydroxylase.
Yazar:: Mole, D, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

The use of dioxygen by HIF prolyl hydroxylase (PHD1).
Yazar:: McNeill, L, ve diğerleri
Baskı/Yayın Bilgisi: (2002)

Determination and comparison of specific activity of the HIF-prolyl hydroxylases.
Yazar:: Tuckerman, JR, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases.
Yazar:: Schlemminger, I, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

The HIF prolyl hydroxylase PHD3 is a potential substrate of the TRiC chaperonin.
Yazar:: Masson, N, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates
Yazar:: Cockman, M, ve diğerleri
Baskı/Yayın Bilgisi: (2019)

Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH).
Yazar:: Cockman, M, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
Yazar:: Chowdhury, R, ve diğerleri
Baskı/Yayın Bilgisi: (2016)

Characterization of different isoforms of the HIF prolyl hydroxylase PHD1 generated by alternative initiation.
Yazar:: Tian, Y, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Molecular and Cellular Mechanisms of HIF Prolyl Hydroxylase inhibitors in Clinical Trials
Yazar:: Yeh, TL, ve diğerleri
Baskı/Yayın Bilgisi: (2017)

Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases.
Yazar:: Chowdhury, R, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

Tissue expression and functional insights into HIF prolyl hydroxylase domain enzymes
Yazar:: Wijeyekoon, JB
Baskı/Yayın Bilgisi: (2013)

Prolyl hydroxylases and therapeutics.
Yazar:: Smith, T, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion.
Yazar:: Yeoh, K, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation.
Yazar:: Willam, C, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Structural, biochemical and inhibition studies on hypoxia-inducible factor (HIF) prolyl hydroxylases
Yazar:: Lippl, K
Baskı/Yayın Bilgisi: (2018)

Impact of HIF prolyl hydroxylase inhibitors in heart failure patients with renal anemia
Yazar:: Takahiro Kambara, ve diğerleri
Baskı/Yayın Bilgisi: (2024-03-01)

Structure–activity relationship and crystallographic studies on 4-hydroxypyrimidine HIF prolyl hydroxylase domain inhibitors
Yazar:: Holt-Martyn, JP, ve diğerleri
Baskı/Yayın Bilgisi: (2019)

Oxygen sensing by HIF hydroxylases.
Yazar:: Schofield, C, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Signalling hypoxia by HIF hydroxylases.
Yazar:: Schofield, C, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity.
Yazar:: Foxler, D, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Kinetic investigations of the oxygen entry pathway of the hypoxia-inducible factor (HIF) prolyl hydroxylase 2
Yazar:: Kearney, L
Baskı/Yayın Bilgisi: (2015)

The HIF hydroxylase pathway and the tumour microenvironment
Yazar:: Ratcliffe, P
Baskı/Yayın Bilgisi: (2008)

Hypoxia-inducible factor prolyl-hydroxylase: purification and assays of PHD2.
Yazar:: Hewitson, K, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice.
Yazar:: Chen, R, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice
Yazar:: Chen, R, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents.
Yazar:: Flashman, E, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Mutation analysis of HIF prolyl hydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibility.
Yazar:: Astuti, D, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

A fluorescent benzo[g]isoquinoline-based HIF prolyl hydroxylase inhibitor for cellular imaging
Yazar:: Mayer, M, ve diğerleri
Baskı/Yayın Bilgisi: (2018)

Mutation Analysis of HIF-prolyl hydroxylases (PHD/EGLN) in Inherited Phaeochromocytoma and Renal Cell Carcinoma
Yazar:: Astuti, D, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

miR-190 Enhances HIF-Dependent Responses to Hypoxia in Drosophila by Inhibiting the Prolyl-4-hydroxylase Fatiga.
Yazar:: Ana Laura De Lella Ezcurra, ve diğerleri
Baskı/Yayın Bilgisi: (2016-05-01)

Differential prolyl hydroxylation by six Physcomitrella prolyl-4 hydroxylases
Yazar:: Christine Rempfer, ve diğerleri
Baskı/Yayın Bilgisi: (2024-12-01)

Substrate selectivity of prolyl hydroxylases
Yazar:: McDonough, M
Baskı/Yayın Bilgisi: (2018)

Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
Yazar:: Stolze, I, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Synthesis And Characterization Of Potential Human Hypoxia Inducible Factor (Hif) Prolyl Hydroxylase Domain 2 (Phd-2) Inhibitors
Yazar:: Toh, Lee Roy
Baskı/Yayın Bilgisi: (2021)

Expression of prolyl-hydroxylases PHD-1, 2 and 3 and of the asparagine hydroxylase FIH in non-small cell lung cancer relates to an activated HIF pathway.
Yazar:: Giatromanolaki, A, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Expression of prolyl-hydroxylases PHD-1, 2 and 3 and of the asparagine hydroxylase FIH in non-small cell lung cancer relates to an activated HIF pathway
Yazar:: Giatromanolaki, A, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Structural and mechanistic studies on prolyl hydroxylases
Yazar:: Chowdhury, R
Baskı/Yayın Bilgisi: (2008)