Soluble CD38 significantly prolongs the lifespan of memory B-cell responses.

The development and maintenance of memory B cells (MBC) is dependent on germinal centres (GC) with follicular dendritic cell (FDC) networks. We have previously shown that FDC networks within GC of the spleen express a novel ligand for CD38 and that the administration of soluble CD38 induces an expan...

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Hlavní autoři: Liu, X, Hart, D, Macpherson, G, Good, M, Wykes, M
Médium: Journal article
Jazyk:English
Vydáno: 2008