RANTES: a versatile and controversial chemokine.
The activity of the chemokine RANTES is not restricted merely to chemotaxis. It is a powerful leukocyte activator, a feature potentially relevant in a range of inflammatory disorders. RANTES has attracted attention because it can potently suppress and, in some circumstances, enhance HIV replication....
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
2001
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_version_ | 1797100466851545088 |
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author | Appay, V Rowland-Jones, S |
author_facet | Appay, V Rowland-Jones, S |
author_sort | Appay, V |
collection | OXFORD |
description | The activity of the chemokine RANTES is not restricted merely to chemotaxis. It is a powerful leukocyte activator, a feature potentially relevant in a range of inflammatory disorders. RANTES has attracted attention because it can potently suppress and, in some circumstances, enhance HIV replication. These characteristics are critically dependent on its ability to self-aggregate and bind to glycosaminoglycans. |
first_indexed | 2024-03-07T05:37:55Z |
format | Journal article |
id | oxford-uuid:e48e08ad-1ae1-44c4-a800-adbcbd741fae |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T05:37:55Z |
publishDate | 2001 |
record_format | dspace |
spelling | oxford-uuid:e48e08ad-1ae1-44c4-a800-adbcbd741fae2022-03-27T10:17:30ZRANTES: a versatile and controversial chemokine.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e48e08ad-1ae1-44c4-a800-adbcbd741faeEnglishSymplectic Elements at Oxford2001Appay, VRowland-Jones, SThe activity of the chemokine RANTES is not restricted merely to chemotaxis. It is a powerful leukocyte activator, a feature potentially relevant in a range of inflammatory disorders. RANTES has attracted attention because it can potently suppress and, in some circumstances, enhance HIV replication. These characteristics are critically dependent on its ability to self-aggregate and bind to glycosaminoglycans. |
spellingShingle | Appay, V Rowland-Jones, S RANTES: a versatile and controversial chemokine. |
title | RANTES: a versatile and controversial chemokine. |
title_full | RANTES: a versatile and controversial chemokine. |
title_fullStr | RANTES: a versatile and controversial chemokine. |
title_full_unstemmed | RANTES: a versatile and controversial chemokine. |
title_short | RANTES: a versatile and controversial chemokine. |
title_sort | rantes a versatile and controversial chemokine |
work_keys_str_mv | AT appayv rantesaversatileandcontroversialchemokine AT rowlandjoness rantesaversatileandcontroversialchemokine |