Statistical challenges in the detection of mutation and variation using high throughput sequencing
The aim of this thesis is to obtain a better understanding of mutation rates within as well as between the genomes of humans and chimpanzees using data generated by high throughput sequencers. I will start with a review of the field and an overview of the technologies and protocols used to generate...
Auteur principal: | Pfeifer, S |
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Autres auteurs: | McVean, G |
Format: | Thèse |
Langue: | English |
Publié: |
2012
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Sujets: |
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