Statistical challenges in the detection of mutation and variation using high throughput sequencing

Statistical challenges in the detection of mutation and variation using high throughput sequencing

The aim of this thesis is to obtain a better understanding of mutation rates within as well as between the genomes of humans and chimpanzees using data generated by high throughput sequencers. I will start with a review of the field and an overview of the technologies and protocols used to generate...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoir:	Pfeifer, S
Rannpháirtithe:	McVean, G
Formáid:	Tráchtas
Teanga:	English
Foilsithe / Cruthaithe:	2012
Ábhair:	Genetics (life sciences) Mathematical genetics and bioinformatics (statistics) Bioinformatics (life sciences)

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