Statistical challenges in the detection of mutation and variation using high throughput sequencing
The aim of this thesis is to obtain a better understanding of mutation rates within as well as between the genomes of humans and chimpanzees using data generated by high throughput sequencers. I will start with a review of the field and an overview of the technologies and protocols used to generate...
Autor Principal: | Pfeifer, S |
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Outros autores: | McVean, G |
Formato: | Thesis |
Idioma: | English |
Publicado: |
2012
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Subjects: |
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