Statistical challenges in the detection of mutation and variation using high throughput sequencing

Statistical challenges in the detection of mutation and variation using high throughput sequencing

The aim of this thesis is to obtain a better understanding of mutation rates within as well as between the genomes of humans and chimpanzees using data generated by high throughput sequencers. I will start with a review of the field and an overview of the technologies and protocols used to generate...

書誌詳細
第一著者:	Pfeifer, S
その他の著者:	McVean, G
フォーマット:	学位論文
言語:	English
出版事項:	2012
主題:	Genetics (life sciences) Mathematical genetics and bioinformatics (statistics) Bioinformatics (life sciences)

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