Statistical challenges in the detection of mutation and variation using high throughput sequencing

The aim of this thesis is to obtain a better understanding of mutation rates within as well as between the genomes of humans and chimpanzees using data generated by high throughput sequencers. I will start with a review of the field and an overview of the technologies and protocols used to generate...

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Bibliografische gegevens
Hoofdauteur: Pfeifer, S
Andere auteurs: McVean, G
Formaat: Thesis
Taal:English
Gepubliceerd in: 2012
Onderwerpen:

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