Statistical challenges in the detection of mutation and variation using high throughput sequencing
The aim of this thesis is to obtain a better understanding of mutation rates within as well as between the genomes of humans and chimpanzees using data generated by high throughput sequencers. I will start with a review of the field and an overview of the technologies and protocols used to generate...
主要作者: | Pfeifer, S |
---|---|
其他作者: | McVean, G |
格式: | Thesis |
語言: | English |
出版: |
2012
|
主題: |
相似書籍
-
An integrated genomic approach for the identification and analysis of single nucleotide polymorphisms that affect cancer in humans
由: Repapi, E
出版: (2013) -
The estimation of recombination rates from population genetic data
由: Auton, A
出版: (2007) -
Application of the Neutral Indel Model to genome sequences for diverse metazoans
由: Meader, S
出版: (2010) -
A method for the identification of biological pathways
由: Honti, F
出版: (2014) -
Statistical HLA type imputation from large and heterogeneous datasets
由: Dilthey, A
出版: (2012)