Statistical challenges in the detection of mutation and variation using high throughput sequencing

The aim of this thesis is to obtain a better understanding of mutation rates within as well as between the genomes of humans and chimpanzees using data generated by high throughput sequencers. I will start with a review of the field and an overview of the technologies and protocols used to generate...

Ausführliche Beschreibung

Bibliographische Detailangaben
1. Verfasser: Pfeifer, S
Weitere Verfasser: McVean, G
Format: Abschlussarbeit
Sprache:English
Veröffentlicht: 2012
Schlagworte: