Statistical challenges in the detection of mutation and variation using high throughput sequencing

The aim of this thesis is to obtain a better understanding of mutation rates within as well as between the genomes of humans and chimpanzees using data generated by high throughput sequencers. I will start with a review of the field and an overview of the technologies and protocols used to generate...

Täydet tiedot

Bibliografiset tiedot
Päätekijä: Pfeifer, S
Muut tekijät: McVean, G
Aineistotyyppi: Opinnäyte
Kieli:English
Julkaistu: 2012
Aiheet: