Statistical challenges in the detection of mutation and variation using high throughput sequencing

The aim of this thesis is to obtain a better understanding of mutation rates within as well as between the genomes of humans and chimpanzees using data generated by high throughput sequencers. I will start with a review of the field and an overview of the technologies and protocols used to generate...

תיאור מלא

מידע ביבליוגרפי
מחבר ראשי: Pfeifer, S
מחברים אחרים: McVean, G
פורמט: Thesis
שפה:English
יצא לאור: 2012
נושאים: