A common neurobiology for pain and pleasure.
Pain and pleasure are powerful motivators of behaviour and have historically been considered opposites. Emerging evidence from the pain and reward research fields points to extensive similarities in the anatomical substrates of painful and pleasant sensations. Recent molecular-imaging and animal stu...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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2008
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| _version_ | 1797100484101668864 |
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| author | Leknes, S Tracey, I |
| author_facet | Leknes, S Tracey, I |
| author_sort | Leknes, S |
| collection | OXFORD |
| description | Pain and pleasure are powerful motivators of behaviour and have historically been considered opposites. Emerging evidence from the pain and reward research fields points to extensive similarities in the anatomical substrates of painful and pleasant sensations. Recent molecular-imaging and animal studies have demonstrated the important role of the opioid and dopamine systems in modulating both pain and pleasure. Understanding the mutually inhibitory effects that pain and reward processing have on each other, and the neural mechanisms that underpin such modulation, is important for alleviating unnecessary suffering and improving well-being. |
| first_indexed | 2024-03-07T05:38:11Z |
| format | Journal article |
| id | oxford-uuid:e4a4a2c1-3f61-4d65-82c1-2b5b3bb848b3 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:38:11Z |
| publishDate | 2008 |
| record_format | dspace |
| spelling | oxford-uuid:e4a4a2c1-3f61-4d65-82c1-2b5b3bb848b32022-03-27T10:18:06ZA common neurobiology for pain and pleasure.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e4a4a2c1-3f61-4d65-82c1-2b5b3bb848b3EnglishSymplectic Elements at Oxford2008Leknes, STracey, IPain and pleasure are powerful motivators of behaviour and have historically been considered opposites. Emerging evidence from the pain and reward research fields points to extensive similarities in the anatomical substrates of painful and pleasant sensations. Recent molecular-imaging and animal studies have demonstrated the important role of the opioid and dopamine systems in modulating both pain and pleasure. Understanding the mutually inhibitory effects that pain and reward processing have on each other, and the neural mechanisms that underpin such modulation, is important for alleviating unnecessary suffering and improving well-being. |
| spellingShingle | Leknes, S Tracey, I A common neurobiology for pain and pleasure. |
| title | A common neurobiology for pain and pleasure. |
| title_full | A common neurobiology for pain and pleasure. |
| title_fullStr | A common neurobiology for pain and pleasure. |
| title_full_unstemmed | A common neurobiology for pain and pleasure. |
| title_short | A common neurobiology for pain and pleasure. |
| title_sort | common neurobiology for pain and pleasure |
| work_keys_str_mv | AT lekness acommonneurobiologyforpainandpleasure AT traceyi acommonneurobiologyforpainandpleasure AT lekness commonneurobiologyforpainandpleasure AT traceyi commonneurobiologyforpainandpleasure |