JmjC-domain-containing proteins and histone demethylation.
Histone methylation has important roles in regulating gene expression and forms part of the epigenetic memory system that regulates cell fate and identity. Enzymes that directly remove methyl marks from histones have recently been identified, revealing a new level of plasticity within this epigeneti...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2006
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| _version_ | 1826301832065974272 |
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| author | Klose, R Kallin, E Zhang, Y |
| author_facet | Klose, R Kallin, E Zhang, Y |
| author_sort | Klose, R |
| collection | OXFORD |
| description | Histone methylation has important roles in regulating gene expression and forms part of the epigenetic memory system that regulates cell fate and identity. Enzymes that directly remove methyl marks from histones have recently been identified, revealing a new level of plasticity within this epigenetic modification system. Here we analyse the evolutionary relationship between Jumonji C (JmjC)-domain-containing proteins and discuss their cellular functions in relation to their potential enzymatic activities. |
| first_indexed | 2024-03-07T05:38:20Z |
| format | Journal article |
| id | oxford-uuid:e4b1baa9-5c1e-466b-b94d-953c9f302cea |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:38:20Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | oxford-uuid:e4b1baa9-5c1e-466b-b94d-953c9f302cea2022-03-27T10:18:27ZJmjC-domain-containing proteins and histone demethylation.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e4b1baa9-5c1e-466b-b94d-953c9f302ceaEnglishSymplectic Elements at Oxford2006Klose, RKallin, EZhang, YHistone methylation has important roles in regulating gene expression and forms part of the epigenetic memory system that regulates cell fate and identity. Enzymes that directly remove methyl marks from histones have recently been identified, revealing a new level of plasticity within this epigenetic modification system. Here we analyse the evolutionary relationship between Jumonji C (JmjC)-domain-containing proteins and discuss their cellular functions in relation to their potential enzymatic activities. |
| spellingShingle | Klose, R Kallin, E Zhang, Y JmjC-domain-containing proteins and histone demethylation. |
| title | JmjC-domain-containing proteins and histone demethylation. |
| title_full | JmjC-domain-containing proteins and histone demethylation. |
| title_fullStr | JmjC-domain-containing proteins and histone demethylation. |
| title_full_unstemmed | JmjC-domain-containing proteins and histone demethylation. |
| title_short | JmjC-domain-containing proteins and histone demethylation. |
| title_sort | jmjc domain containing proteins and histone demethylation |
| work_keys_str_mv | AT kloser jmjcdomaincontainingproteinsandhistonedemethylation AT kalline jmjcdomaincontainingproteinsandhistonedemethylation AT zhangy jmjcdomaincontainingproteinsandhistonedemethylation |