Dysregulation of glucagon secretion by hyperglycemia-induced sodium-dependent reduction of ATP production

Diabetes is a bihormonal disorder resulting from combined insulin and glucagon secretion defects. Mice lacking fumarase (Fh1) in their β cells (Fh1βKO mice) develop progressive hyperglycemia and dysregulated glucagon secretion similar to that seen in diabetic patients (too much at high glucose and t...

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গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Knudsen, JG, Hamilton, A, Ramracheya, R, Tarasov, AI, Brereton, M, Haythorne, E, Chibalina, MV, Spégel, P, Mulder, H, Zhang, Q, Ashcroft, FM, Adam, J, Rorsman, P
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: Elsevier 2018