HLA-B27 homodimers and free H chains are stronger ligands for leukocyte Ig-like receptor B2 than classical HLA class I.

Possession of HLA-B27 (B27) strongly predisposes to the development of spondyloarthritis. B27 forms classical heterotrimeric complexes with β(2)-microglobulin (β2m) and peptide and (β2m free) free H chain (FHC) forms including B27 dimers (termed B27(2)) at the cell surface. In this study, we charact...

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Những tác giả chính: Giles, J, Shaw, J, Piper, C, Wong-Baeza, I, McHugh, K, Ridley, A, Li, D, Lenart, I, Antoniou, A, DiGleria, K, Kuroki, K, Maenaka, K, Bowness, P, Kollnberger, S
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2012