Recent advances in the biology of tumour hypoxia with relevance to diagnostic practice and tissue‐based research
In this review article, we examine the importance of low levels of oxygen (hypoxia) in cancer biology. We provide a brief description of how mammalian cells sense oxygen. The hypoxia-inducible factor (HIF) pathway is currently the best characterised oxygen sensing system, but recent work has reveale...
Main Authors: | Macklin, PS, Yamamoto, A, Browning, L, Hofer, M, Adam, J, Christopher W Pugh |
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Format: | Journal article |
Language: | English |
Published: |
Wiley
2020
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