Recent advances in the biology of tumour hypoxia with relevance to diagnostic practice and tissue‐based research

In this review article, we examine the importance of low levels of oxygen (hypoxia) in cancer biology. We provide a brief description of how mammalian cells sense oxygen. The hypoxia-inducible factor (HIF) pathway is currently the best characterised oxygen sensing system, but recent work has reveale...

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Bibliographic Details
Main Authors: Macklin, PS, Yamamoto, A, Browning, L, Hofer, M, Adam, J, Christopher W Pugh
Format: Journal article
Language:English
Published: Wiley 2020

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