Proportion and phenotype of MYH-associated colorectal neoplasia in a population-based series of Finnish colorectal cancer patients.

Proportion and phenotype of MYH-associated colorectal neoplasia in a population-based series of Finnish colorectal cancer patients.

Recessively inherited mutations in the base excision repair gene MYH have recently been associated with predisposition to colorectal adenomas and cancer in materials selected for occurrence of multiple adenomas. In particular, variants Y165C and G382D have been shown to play a role in Caucasian pati...

Full description

Bibliographic Details
Main Authors:	Enholm, S, Hienonen, T, Suomalainen, A, Lipton, L, Tomlinson, I, Kärjä, V, Eskelinen, M, Mecklin, J, Karhu, A, Järvinen, H, Aaltonen, L
Format:	Journal article
Language:	English
Published:	2003

Similar Items

The multiple colorectal adenoma phenotype and MYH, a base excision repair gene.
by: Lipton, L, et al.
Published: (2004)

Genome-wide allelotyping of 104 Finnish colorectal cancers reveals an excess of allelic imbalance in chromosome 20q in familial cases.
by: Laiho, P, et al.
Published: (2003)

Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH.
by: Sieber, O, et al.
Published: (2003)

The C/C-13910 genotype of adult-type hypolactasia is associated with an increased risk of colorectal cancer in the Finnish population.
by: Rasinperä, H, et al.
Published: (2005)

Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci.
by: Niittymäki, I, et al.
Published: (2011)

Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers.
by: Halford, SE, et al.
Published: (2003)

MYH7 Genotype–Phenotype Correlation in a Cohort of Finnish Patients
by: Teemu Vepsäläinen, et al.
Published: (2022-03-01)

Numbers of mutations to different types of colorectal cancer
by: Tavaré Simon, et al.
Published: (2005-10-01)

Somatic mutation analysis of <it>MYH11 </it>in breast and prostate cancer
by: Waltering Kati, et al.
Published: (2008-09-01)

EPHB2 germline variants in patients with colorectal cancer or hyperplastic polyposis
by: Kokko, A, et al.
Published: (2006)

Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH/MUTYH mutations.
by: Thirlwell, C, et al.
Published: (2007)

Myh deficiency enhances intestinal tumorigenesis in multiple intestinal neoplasia (ApcMin/+) mice.
by: Sieber, O, et al.
Published: (2004)

Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway.
by: Lipton, L, et al.
Published: (2003)

Aspirin in the chemoprevention of colorectal neoplasia: an overview.
by: Chan, A, et al.
Published: (2012)

Top down or bottom up morphogenesis of colorectal adenomas: Competing management structures in the origins of colorectal neoplasia
by: Preston, S, et al.
Published: (2003)

Screening of Finnish <it>RAD51C</it> founder mutations in prostate and colorectal cancer patients
by: Pelttari Liisa M, et al.
Published: (2012-11-01)

Unregulated smooth-muscle myosin in human intestinal neoplasia.
by: Alhopuro, P, et al.
Published: (2008)

Bacterial Involvement in Progression and Metastasis of Colorectal Neoplasia
by: Kevin D. Seely, et al.
Published: (2022-02-01)

Advanced colorectal neoplasia: The importance of adequate classification
by: A. Parra del Riego, et al.
Published: (2016-04-01)

Phosphoinositide signalling in inflammatory bowel disease and colorectal neoplasia
by: Osborne, C, et al.
Published: (2002)

Molecular genetics of colorectal neoplasia : a primer for the clinician /
by: Church, James M., et al.
Published: (2004)

Advanced colorectal neoplasia: Response to Parra del Riego
by: V. Parra-Pérez, et al.
Published: (2016-04-01)

Fecal DNA Virome Is Associated with the Development of Colorectal Neoplasia in a Murine Model of Colorectal Cancer
by: Yingshi Li, et al.
Published: (2022-04-01)

Defining the clinical phenotype of hereditary nonpolyposis colorectal cancer
by: Beck, N, et al.
Published: (1999)

MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions.
by: Lefevre, J, et al.
Published: (2010)

The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling.
by: Tuupanen, S, et al.
Published: (2009)

Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP.
by: Cheng, T, et al.
Published: (2014)

Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia
by: Gil Vasquez, E, et al.
Published: (2022)

Colorectal tumourigenesis in carriers of the APC I1307K variant: lone gunman or conspiracy?
by: Sieber, O, et al.
Published: (2003)

An adjusted Asia-Pacific colorectal screening score system to predict advanced colorectal neoplasia in asymptomatic Chinese patients
by: Chenchen Zhang, et al.
Published: (2023-06-01)

Insulin-like growth factor I and the development of colorectal neoplasia in acromegaly.
by: Jenkins, P, et al.
Published: (2000)

Association between calcium intake and colorectal neoplasia in Puerto Rican Hispanics
by: Cristina Palacios, et al.

Increased prevalence of colorectal neoplasia in patients with intraductal papillary mucinous neoplasms
by: Dana Zelnik Yovel, et al.
Published: (2022-06-01)

A prediction model for advanced colorectal neoplasia in an asymptomatic screening population.
by: Sung Noh Hong, et al.
Published: (2017-01-01)

Association between calcium intake and colorectal neoplasia in Puerto Rican Hispanics Asociación entre el consumo de calcio y la neoplasia colorectal en hispanos puertorriqueños
by: Cristina Palacios, et al.
Published: (2010-12-01)

Validation of the Asia-Pacific colorectal screening score and its modified versions in predicting colorectal advanced neoplasia in Chinese population
by: Yunxin Kong, et al.
Published: (2022-09-01)

Top-down or bottom-up morphogenesis of colorectal adenomas: Competing management structures in the origins of colonic neoplasia
by: Preston, S, et al.
Published: (2003)

A case of MYH7 and MYH9 genes variants with cardiomyopathy and macrothrombocytopenia
by: Yasuhiro Ikawa, et al.
Published: (2024-02-01)

Same MYH7 gene mutation but different phenotypes of cardiomyopathy in one family
by: Ting Liu, et al.
Published: (2023-10-01)

The frequency of NRAS mutation in stool samples of Iranian colorectal cancers compared to Finnish patients
by: Farideh Saberi, et al.
Published: (2024-01-01)