Preexisting influenza-specific CD4 + T cells correlate with disease protection against influenza challenge in humans

Protective immunity against influenza virus infection is mediated by neutralizing antibodies, but the precise role of T cells in human influenza immunity is uncertain. We conducted influenza infection studies in healthy volunteers with no detectable antibodies to the challenge viruses H3N2 or H1N1....

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Үндсэн зохиолчид:	Wilkinson, T, Li, C, Chui, C, Huang, A, Perkins, M, Liebner, J, Lambkin-Williams, R, Gilbert, A, Oxford, J, Nicholas, B, Staples, K, Dong, T, Douek, D, McMichael, A, Xu, X
Формат:	Journal article
Хэвлэсэн:	2012

Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans. -н Wilkinson, T, Li, C, Chui, C, Huang, A, Perkins, M, Liebner, J, Lambkin-Williams, R, Gilbert, A, Oxford, J, Nicholas, B, Staples, K, Dong, T, Douek, D, Mcmichael, A, Xu, X

Хэвлэсэн 2012

Journal article

Preexisting influenza-specific CD4 + T cells correlate with disease protection against influenza challenge in humans

Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans. -н Wilkinson, T, Li, C, Chui, C, Huang, A, Perkins, M, Liebner, J, Lambkin-Williams, R, Gilbert, A, Oxford, J, Nicholas, B, Staples, K, Dong, T, Douek, D, Mcmichael, A, Xu, X

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