An intronic Runx1 enhancer directs transcription to the emerging hematopoietic system of the mouse embryo

Geahča maid

• Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer.
  Dahkki: Nottingham, W, et al.
  Almmustuhtton: (2007)
• The mouse Runx1 +23 hematopoietic stem cell enhancer confers hematopoietic specificity to both Runx1 promoters.
  Dahkki: Bee, T, et al.
  Almmustuhtton: (2009)
• Hematopoietic stem cell emergence in the conceptus and the role of Runx1.
  Dahkki: Swiers, G, et al.
  Almmustuhtton: (2010)
• Runx1 is expressed in adult mouse hematopoietic stem cells and differentiating myeloid and lymphoid cells, but not in maturing erythroid cells.
  Dahkki: North, T, et al.
  Almmustuhtton: (2004)
• DISTINCT RUNX1 ENHANCERS DIRECT TRANSCRIPTION TO DISCRETE STAGES OF DEVELOPMENTAL HEMATOPOIESIS
  Dahkki: O'Rourke, J, et al.
  Almmustuhtton: (2012)