Loss of endogenous bone morphogenetic protein-6 aggravates renal fibrosis.

Loss of endogenous bone morphogenetic protein-6 aggravates renal fibrosis.

Bone morphogenetic protein-6 (BMP-6) suppresses inflammatory genes in renal proximal tubular cells and regulates iron metabolism by inducing hepcidin. In diabetic patients, an increase of myofibroblast progenitor cells (MFPCs), also known as fibrocytes, was found to be associated with decreased BMP-...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän:	Dendooven, A, van Oostrom, O, van der Giezen, D, Leeuwis, J, Snijckers, C, Joles, J, Robertson, E, Verhaar, M, Nguyen, T, Goldschmeding, R
Materialtyp:	Journal article
Språk:	English
Publicerad:	2011

Liknande verk

Role of bone morphogenetic protein-7 in renal fibrosis
av: Rui Xi eLi, et al.
Publicerad: (2015-04-01)

Loss of PTPN21 disrupted mitochondrial metabolic homeostasis and aggravated experimental pulmonary fibrosis
av: Hui Lian, et al.
Publicerad: (2024-12-01)

Combination of bone morphogenetic protein-2 plasmid DNA with chemokine
av: F Wegman, et al.
Publicerad: (2015-07-01)

Bone morphogenetic protein signaling protects against cerulein-induced pancreatic fibrosis.
av: Xuxia Gao, et al.
Publicerad: (2014-01-01)

Krüppel-like factor 6 mediates pulmonary angiogenesis in rat experimental hepatopulmonary syndrome and is aggravated by bone morphogenetic protein 9
av: Yihui Yang, et al.
Publicerad: (2019-06-01)

Endogenous FGF1 Deficiency Aggravates Doxorubicin-Induced Hepatotoxicity
av: Chunjie Gu, et al.
Publicerad: (2023-11-01)

Healthy Bone Marrow Cells Reduce Progression of Kidney Failure Better than CKD Bone Marrow Cells in Rats with Established Chronic Kidney Disease
av: Arianne Van Koppen, et al.
Publicerad: (2012-10-01)

Bone morphogenetic protein 7 mediates stem cells migration and angiogenesis: therapeutic potential for endogenous pulp regeneration
av: Cheng Liang, et al.
Publicerad: (2022-07-01)

Loss of bone morphogenetic protein-binding endothelial regulator causes insulin resistance
av: Hua Mao, et al.
Publicerad: (2021-03-01)

Myeloid DNA methyltransferase3b deficiency aggravates pulmonary fibrosis by enhancing profibrotic macrophage activation
av: Wanhai Qin, et al.
Publicerad: (2022-06-01)

Akt inhibitor deguelin aggravates inflammation and fibrosis in myocarditis
av: Shanshan Li, et al.
Publicerad: (2019-11-01)

Salivary microbiota of periodontitis aggravates bone loss in ovariectomized rats
av: Nannan Wang, et al.
Publicerad: (2022-08-01)

Inhibition of PTEN Activity Aggravates Post Renal Fibrosis in Mice with Ischemia Reperfusion-Induced Acute Kidney Injury
av: Jun Zhou, et al.
Publicerad: (2017-10-01)

Modulation of bone morphogenetic protein-2 and bone morphogenetic protein-4 gene expression in osteoblastic cell lines.
av: Virdi, A, et al.
Publicerad: (1998)

Current Topics in Pharmacological Research on Bone Metabolism: Regulation of Bone Mass by the Function of Endogenous Modulators of Bone Morphogenetic Protein in Adult Stage
av: Masaki Noda
Publicerad: (2006-01-01)

Nuclear variants of bone morphogenetic proteins
av: Meinhart Christopher A, et al.
Publicerad: (2010-03-01)

Bone morphogenetic protein-4 and bone morphogenetic protein receptors expressions in the adult rat eye
av: Yuka Maruyama-Koide, et al.
Publicerad: (2017-09-01)

Circulating bone morphogenetic protein 8A is a novel biomarker to predict advanced liver fibrosis
av: Patricia Marañón, et al.
Publicerad: (2023-04-01)

miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7Research in context
av: Meng Wang, et al.
Publicerad: (2019-03-01)

Endogenous Bufadienolides, Fibrosis and Preeclampsia
av: Vitaliy A. Reznik, et al.
Publicerad: (2019-01-01)

CCN2 Aggravates the Immediate Oxidative Stress–DNA Damage Response following Renal Ischemia–Reperfusion Injury
av: Floris A. Valentijn, et al.
Publicerad: (2021-12-01)

Maternal undernutrition aggravates renal tubular necrosis and interstitial fibrosis after unilateral ureteral obstruction in male rat offspring.
av: Midori Awazu, et al.
Publicerad: (2019-01-01)

VISTA Blockade Aggravates Bone Loss in Experimental Murine Apical Periodontitis
av: Fuhua Yang, et al.
Publicerad: (2021-10-01)

Protein targeting protocols /
av: Van Der Giezen, Mark
Publicerad: (2007)

Antiviral activity of bone morphogenetic proteins and activins
av: Eddowes, LA, et al.
Publicerad: (2018)

Possible Involvement of Endogenous 5-HT in Aggravation of Cerulein-Induced Acute Pancreatitis in Mice
av: Kentaro Hamada, et al.
Publicerad: (2007-01-01)

Cercosporamide inhibits bone morphogenetic protein receptor type I kinase activity in zebrafish
av: Jelmer Hoeksma, et al.
Publicerad: (2020-09-01)

LACK OF ASSOCIATION OF BONE MORPHOGENETIC PROTEIN 2 GENE HAPLOTYPES WITH BONE MINERAL DENSITY, BONE LOSS OR RISK OF FRACTURES IN MEN
av: Varanasi, S, et al.
Publicerad: (2009)

Morphogenetic landscapes :
av: Taylor, Daniel G. (Daniel Glenn)
Publicerad: (2015)

Bone Morphogenetic Proteins and Diabetic Retinopathy
av: Khaled Elmasry, et al.
Publicerad: (2021-04-01)

Bone morphogenetic proteins: The anomalous molecules
av: Aena Pundir Jain, et al.
Publicerad: (2013-01-01)

Aggravated renal fibrosis is positively associated with the activation of HMGB1-TLR2/4 signaling in STZ-induced diabetic mice
av: Yuan Yan, et al.
Publicerad: (2022-11-01)

Jmjd3/IRF4 axis aggravates myeloid fibroblast activation and m2 macrophage to myofibroblast transition in renal fibrosis
av: Hua Liang, et al.
Publicerad: (2022-09-01)

Cavin‐2 promotes fibroblast‐to‐myofibroblast trans‐differentiation and aggravates cardiac fibrosis
av: Yusuke Higuchi, et al.
Publicerad: (2024-02-01)

EVIDENCE THAT ENDOGENOUS CALCITONIN PROTECTS AGAINST RENAL BONE-DISEASE
av: Heynen, G, et al.
Publicerad: (1976)

Bone morphogenetic proteins: from structure to clinical use
av: Granjeiro J.M., et al.
Publicerad: (2005-01-01)

Micellized Protein Transduction Domain-Bone Morphogenetic Protein-7 Efficiently Blocks Renal Fibrosis Via Inhibition of Transforming Growth Factor-Beta–Mediated Epithelial–Mesenchymal Transition
av: Seonghun Kim, et al.
Publicerad: (2020-11-01)

Interleukin 17 enhances bone morphogenetic protein-2-induced ectopic bone formation
av: M. Croes, et al.
Publicerad: (2018-05-01)

Aggravated hepatic fibrosis induced by phenylalanine and tyrosine was ameliorated by chitooligosaccharides supplementation
av: Peng Liu, et al.
Publicerad: (2023-10-01)

Estrogen aggravates inflammation in <it>Pseudomonas aeruginosa </it>pneumonia in cystic fibrosis mice
av: Gagnon Stéphane, et al.
Publicerad: (2010-11-01)