Loss of endogenous bone morphogenetic protein-6 aggravates renal fibrosis.

Loss of endogenous bone morphogenetic protein-6 aggravates renal fibrosis.

Bone morphogenetic protein-6 (BMP-6) suppresses inflammatory genes in renal proximal tubular cells and regulates iron metabolism by inducing hepcidin. In diabetic patients, an increase of myofibroblast progenitor cells (MFPCs), also known as fibrocytes, was found to be associated with decreased BMP-...

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Bibliografiske detaljer
Main Authors:	Dendooven, A, van Oostrom, O, van der Giezen, D, Leeuwis, J, Snijckers, C, Joles, J, Robertson, E, Verhaar, M, Nguyen, T, Goldschmeding, R
Format:	Journal article
Sprog:	English
Udgivet:	2011

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