Matrix metalloproteinase triple-helical peptidase activities are differentially regulated by substrate stability.
Matrix metalloproteinases (MMPs) are involved in physiological remodeling as well as pathological destruction of tissues. The turnover of the collagen triple-helical structure has been ascribed to several members of the MMP family, but the determinants for collagenolytic specificity have not been id...
Main Authors: | Minond, D, Lauer-Fields, J, Nagase, H, Fields, G |
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Format: | Journal article |
Language: | English |
Published: |
2004
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