Matrix metalloproteinase triple-helical peptidase activities are differentially regulated by substrate stability.

Matrix metalloproteinases (MMPs) are involved in physiological remodeling as well as pathological destruction of tissues. The turnover of the collagen triple-helical structure has been ascribed to several members of the MMP family, but the determinants for collagenolytic specificity have not been id...

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Bibliographic Details
Main Authors: Minond, D, Lauer-Fields, J, Nagase, H, Fields, G
Format: Journal article
Language:English
Published: 2004

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