A randomised, double-blind, parallel-group trial to assess mercaptopurine versus placebo to prevent or delay recurrence of Crohn’s disease following surgical resection (TOPPIC)

A randomised, double-blind, parallel-group trial to assess mercaptopurine versus placebo to prevent or delay recurrence of Crohn’s disease following surgical resection (TOPPIC)

<p>Background: Crohn’s disease (CD) is a chronic, relapsing, inflammatory bowel disease. Up to 65% of patients with CD require an operation to control the disease within 10 years. Both endoscopic and clinical recurrence is common within 2 years of operation, with re-operation rates cumulating...

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Bibliographic Details
Main Authors:	Satsangi, J, Kennedy, N, Mowat, C, Arnott, I, Keerie, C, Lewis, S, Ennis, H
Format:	Journal article
Published:	NIHR Journals Library 2017

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