Early antiretroviral therapy reduces hiv dna following perinatal HIV infection

Early antiretroviral therapy reduces hiv dna following perinatal HIV infection

: The impact of antiretroviral therapy (ART) on the size of the HIV reservoir has implications for virological remission in adults, but is not well characterised in perinatally acquired infection (PaHIV). In a prospective observational study of 20 children with PaHIV and sustained viral suppression...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Foster, C, Pace, M, Kaye, S, Hopkins, E, Jones, M, Robinson, N, Fidler, S, Frater, J, CHERUB Investigators
Natura:	Journal article
Lingua:	English
Pubblicazione:	Lippincott, Williams & Wilkins 2017

Documenti analoghi

Impact of antiretroviral therapy in primary HIV infection on natural killer cell function and the association with viral rebound and HIV DNA following treatment interruption
di: Matthew Pace, et al.
Pubblicazione: (2022-08-01)

Control of HIV viraemia is not enough in perinatal HIV
di: Caroline Foster, et al.
Pubblicazione: (2015-07-01)

Enrichment of the HIV reservoir in CD32+CD4 T cells occurs early and is closely associated with immune checkpoint receptor expression
di: Martin, GE, et al.
Pubblicazione: (2017)

Soluble plasma programmed death 1 (PD-1) and Tim-3 in primary HIV infection
di: Frater, J, et al.
Pubblicazione: (2019)

Virological remission after antiretroviral therapy interruption in female African HIV seroconverters
di: Gossez, M, et al.
Pubblicazione: (2018)

Therapeutic vaccination following early antiretroviral therapy elicits highly functional T cell responses against conserved HIV-1 regions
di: Jakub Kopycinski, et al.
Pubblicazione: (2023-10-01)

MRI of perinatal HIV infection in the era of antiretroviral therapy
di: M. A. Titova, et al.
Pubblicazione: (2021-05-01)

Expression of type I interferon-associated genes at antiretroviral therapy interruption predicts HIV virological rebound
di: P. Zacharopoulou, et al.
Pubblicazione: (2022-01-01)

Adults with Perinatally Acquired HIV; Emerging Clinical Outcomes and Data Gaps
di: Merle Henderson, et al.
Pubblicazione: (2024-04-01)

Short-course antiretroviral therapy in primary HIV infection.
di: Fidler, S, et al.
Pubblicazione: (2013)

Epigenetic Features of HIV-Induced T-Cell Exhaustion Persist Despite Early Antiretroviral Therapy
di: Genevieve E. Martin, et al.
Pubblicazione: (2021-06-01)

The impact of immunoglobulin in acute HIV infection on the HIV reservoir: a randomized controlled trial
di: Tiraboschi, J, et al.
Pubblicazione: (2017)

The impact of immunoglobulin in acute HIV infection on the HIV reservoir: a randomized controlled trial
di: Tiraboschi, J, et al.
Pubblicazione: (2017)

Sustained Virologic Suppression Reduces HIV-1 DNA Proviral Levels and HIV Antibodies in Perinatally HIV-Infected Children Followed from Birth
di: Trevon Fuller, et al.
Pubblicazione: (2022-10-01)

Drug monitoring of antiretroviral drugs in children with perinatal HIV infection
di: A. Yu. Sambyalova, et al.
Pubblicazione: (2024-07-01)

A cure for HIV: is it in sight?
di: Pace, M, et al.
Pubblicazione: (2014)

Immunotherapeutic approaches to HIV cure and remission
di: Lee, MJ, et al.
Pubblicazione: (2021)

Antiretroviral therapy alone versus antiretroviral therapy with a kick and kill approach, on measures of the HIV reservoir in participants with recent HIV infection (the RIVER trial): a phase 2, randomised trial
di: Fidler, S, et al.
Pubblicazione: (2020)

CD32 expressing doublets in HIV-infected gut-associated lymphoid tissue are associated with a T follicular helper cell phenotype
di: Thornhill, J, et al.
Pubblicazione: (2019)

Bone mineral density optimisation in adults with perinatally acquired HIV infection in routine care
di: Thomas J. Pasvol, et al.
Pubblicazione: (2017-10-01)

Five-year follow-up of children with perinatal HIV-1 infection receiving early highly active antiretroviral therapy
di: Badolato Raffaele, et al.
Pubblicazione: (2009-08-01)

Childhood lung function following perinatal HIV infection and early antiretroviral therapy initiation: a cross-sectional study
di: Andre Gie, et al.
Pubblicazione: (2022-03-01)

Hospitalisation rates for youth living with perinatally acquired HIV in England.
di: Sarah May Johnson, et al.
Pubblicazione: (2024-01-01)

Early Combination Antiretroviral Therapy Limits Exposure to HIV-1 Replication and Cell-Associated HIV-1 DNA Levels in Infants.
di: Margaret McManus, et al.
Pubblicazione: (2016-01-01)

HIV cure research in the time of COVID-19 - Antiretroviral therapy treatment interruption trials: A discussion paper
di: S. Fidler, et al.
Pubblicazione: (2021-03-01)

Curing HIV by 'kick and kill': from theory to practice?
di: Pace, M, et al.
Pubblicazione: (2019)

Prevalence and Risk Factors for Hepatic Steatosis in Children With Perinatal HIV on Early Antiretroviral Therapy Compared to HIV-Exposed Uninfected and HIV-Unexposed Children
di: Penelope C. Rose, et al.
Pubblicazione: (2022-06-01)

Advancing the HIV cure agenda: the next 5 years.
di: Thornhill, J, et al.
Pubblicazione: (2015)

A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation
di: Avy Violari, et al.
Pubblicazione: (2019-01-01)

A randomised controlled trial comparing the impact of Antiretroviral Therapy (ART) with a ‘Kick-and-Kill’ approach to ART alone on HIV reservoirs in individuals with primary HIV infection (PHI); RIVER trial
di: Fidler, S, et al.
Pubblicazione: (2018)

HIV-1 co-receptor tropism and disease progression in children and young adults with perinatally acquired HIV-1 infection. The HICCUP Study
di: C. Foster, et al.
Pubblicazione: (2015-07-01)

Histone Deacetylase Inhibitors Enhance CD4 T Cell Susceptibility to NK Cell Killing but Reduce NK Cell Function.
di: Matthew Pace, et al.
Pubblicazione: (2016-08-01)

Cardioprotective effects of early versus late initiated antiretroviral treatment in adolescents with perinatal HIV-1 infection
di: Itai M. Magodoro, et al.
Pubblicazione: (2024-06-01)

Malignancy and all-cause mortality; incidence in adolescents and young adults living with perinatally acquired HIV
di: Srishti Chhabra, et al.
Pubblicazione: (2020-01-01)

HIV-1 drug resistance in primary infections in the UK.
di: Fidler, S, et al.
Pubblicazione: (2001)

Case series of infertility amongst young women with perinatally acquired HIV: data from a London cohort
di: Jhia Teh, et al.
Pubblicazione: (2019-01-01)

Paucity of Intact Non-Induced Provirus with Early, Long-Term Antiretroviral Therapy of Perinatal HIV Infection.
di: Kaitlin Rainwater-Lovett, et al.
Pubblicazione: (2017-01-01)

Duration of HIV-1 viral suppression on cessation of antiretroviral therapy in primary infection correlates with time on therapy
di: Stöhr, W, et al.
Pubblicazione: (2013)

Chronic comorbidities in children and adolescents with perinatally acquired HIV infection in sub-Saharan Africa in the era of antiretroviral therapy
di: Frigati, LJ, et al.
Pubblicazione: (2020)

Increased levels of CD4 T-cell activation in individuals with CXCR4 using viruses in primary HIV-1 infection.
di: Hamlyn, E, et al.
Pubblicazione: (2012)