Site-selective modification of peptides using rhodium and palladium catalysis: complementary electrophilic and nucleophilic arylation.

The site-selective modification of peptides containing dehydroalanine, tyrosine and tryptophan residues has been achieved using rhodium catalysed conjugate additions or palladium catalysed aryl-amination and -etherification reactions.

Bibliographische Detailangaben
Hauptverfasser: Chapman, C, Matsuno, A, Frost, C, Willis, M
Format: Journal article
Sprache:English
Veröffentlicht: 2007
Beschreibung
Zusammenfassung:The site-selective modification of peptides containing dehydroalanine, tyrosine and tryptophan residues has been achieved using rhodium catalysed conjugate additions or palladium catalysed aryl-amination and -etherification reactions.