Maternal transmission of a humanised Igf2r allele results in an Igf2 dependent hypomorphic and non-viable growth phenotype

Maternal transmission of a humanised Igf2r allele results in an Igf2 dependent hypomorphic and non-viable growth phenotype

The cation independent mannose 6-phosphate/insulin-like growth factor 2 receptor (IGF2R) functions in the transportation and regulation of insulin-like growth factor 2 (IGF2) and mannose 6-phosphate modified proteins. The relative and specific titration of IGF2 by high affinity binding of IGF2R repr...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Hughes, J, Frago, S, Bühnemann, C, Carter, E, Hassan, A
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	Public Library of Science 2013

Ижил төстэй зүйлс

Maternal transmission of a humanised Igf2r allele results in an Igf2 dependent hypomorphic and non-viable growth phenotype.
-н: Jennifer Hughes, зэрэг
Хэвлэсэн: (2013-01-01)

Maternal transmission of an Igf2r domain 11: IGF2 binding mutant allele (Igf2rI1565A) results in partial lethality, overgrowth and intestinal adenoma progression
-н: Hughes, J, зэрэг
Хэвлэсэн: (2019)

Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes.
-н: Haley, V, зэрэг
Хэвлэсэн: (2012)

Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes
-н: Victoria L. Haley, зэрэг
Хэвлэсэн: (2012-06-01)

Igf2 ligand dependency of Pten(+/-) developmental and tumour phenotypes in the mouse.
-н: Church, D, зэрэг
Хэвлэсэн: (2012)

Igf2 ligand dependency of Pten +- developmental and tumour phenotypes in the mouse
-н: Church, D, зэрэг
Хэвлэсэн: (2012)

Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
-н: Frago, S, зэрэг
Хэвлэсэн: (2016)

Correction: A Viable Hypomorphic Allele of the Essential Gene Reveals Novel Protein Functions in.
-н: Bruno Cosnier, зэрэг
Хэвлэсэн: (2011-01-01)

An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
-н: Williams, C, зэрэг
Хэвлэсэн: (2012)

FBXO7 sensitivity of phenotypic traits elucidated by a hypomorphic allele.
-н: Carmen Ballesteros Reviriego, зэрэг
Хэвлэсэн: (2019-01-01)

Structure and functional analysis of the IGF-II/IGF2R interaction.
-н: Brown, J, зэрэг
Хэвлэсэн: (2008)

Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects
-н: Bard-Chapeau, E, зэрэг
Хэвлэсэн: (2014)

Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.
-н: Emilie A Bard-Chapeau, зэрэг
Хэвлэсэн: (2014-01-01)

A viable hypomorphic allele of the essential IMP3 gene reveals novel protein functions in Saccharomyces cerevisiae.
-н: Bruno Cosnier, зэрэг
Хэвлэсэн: (2011-04-01)

Keeping IGF-II under control: lessons from the IGF-II-IGF2R crystal structure.
-н: Brown, J, зэрэг
Хэвлэсэн: (2009)

Genomic imprinting of <it>IGF2 </it>in marsupials is methylation dependent
-н: Imumorin Ikhide, зэрэг
Хэвлэсэн: (2008-05-01)

The associations of IGF2, IGF2R and IGF2BP2 gene polymorphisms with gestational diabetes mellitus: A case-control study.
-н: Wei Li, зэрэг
Хэвлэсэн: (2024-01-01)

Non-glycosylated IGF2 prohormones are more mitogenic than native IGF2
-н: Pavlo Potalitsyn, зэрэг
Хэвлэсэн: (2023-08-01)

A fasting insulin-raising allele at IGF1 locus is associated with circulating levels of IGF-1 and insulin sensitivity.
-н: Gaia Chiara Mannino, зэрэг
Хэвлэсэн: (2013-01-01)

Genome-wide characterization of three IGFs in hybrid yellow catfish (Pseudobagrus fulvidraco ♀× Pseudobagrus vachellii ♂) and the association of IGF2 allelic variants with growth traits
-н: Mingxu Chu, зэрэг
Хэвлэсэн: (2022-10-01)

Correction: A Viable Hypomorphic Allele of the Essential IMP3 Gene Reveals Novel Protein Functions in Saccharomyces cerevisiae
Хэвлэсэн: (2011-01-01)

IGF2 and IGF1R mRNAs Are Detectable in Human Spermatozoa
-н: Rossella Cannarella, зэрэг
Хэвлэсэн: (2020-10-01)

Interaction between IGF-IR and ER induced by E2 and IGF-I.
-н: Zhenghong Yu, зэрэг
Хэвлэсэн: (2013-01-01)

Paternal bias expression of Igf2as is enhancer-dependent on the imprinting cluster of Igf2, H19 and Nctc1 in muscle cells
-н: Jae-Young Kim, зэрэг
Хэвлэсэн: (2019-07-01)

The Association of Soluble IGF2R and IGF2R Gene Polymorphism with Type 2 Diabetes
-н: Suwannee Chanprasertyothin, зэрэг
Хэвлэсэн: (2015-01-01)

Soluble IGF2 receptor rescues Apc(Min/+) intestinal adenoma progression induced by Igf2 loss of imprinting.
-н: Harper, J, зэрэг
Хэвлэсэн: (2006)

Structure and function of the human Gly1619Arg polymorphism of M6P/IGF2R domain 11 implicated in IGF2 dependent growth.
-н: Rezgui, D, зэрэг
Хэвлэсэн: (2009)

Allele-specific transcriptional elongation regulates monoallelic expression of the <it>IGF2BP1 </it>gene
-н: Thomas Brandon J, зэрэг
Хэвлэсэн: (2011-08-01)

A viable hypomorphic Arnt2 mutation causes hyperphagic obesity, diabetes and hepatic steatosis
-н: Emre E. Turer, зэрэг
Хэвлэсэн: (2018-12-01)

Overexpression of IGF2 affects mouse weight and glycolipid metabolism and IGF2 is positively related to macrosomia
-н: Qidi Zhang, зэрэг
Хэвлэсэн: (2023-04-01)

Different epigenetic alterations are associated with abnormal IGF2/Igf2 upregulation in neural tube defects.
-н: Baoling Bai, зэрэг
Хэвлэсэн: (2014-01-01)

Quantitative allele-specific expression and DNA methylation analysis of H19, IGF2 and IGF2R in the human placenta across gestation reveals H19 imprinting plasticity.
-н: Sam Buckberry, зэрэг
Хэвлэсэн: (2012-01-01)

A novel hypomorphic allele of Spag17 causes primary ciliary dyskinesia phenotypes in mice
-н: Zakia Abdelhamed, зэрэг
Хэвлэсэн: (2020-10-01)

BROILER GENOTYPING AND ALLILIC FREQUNCY ANALYSIS BY PCR-RFLP FOR IGF1 AND IGF2 GENES
-н: Ali S. Al-Hassani
Хэвлэсэн: (2022-10-01)

Overexpression of IGF2 and IGF2 receptor in malignant solitary fibrous tumor with hypoglycemia: a case report
-н: Yusuke Arakawa, зэрэг
Хэвлэсэн: (2018-08-01)

Rare De Novo IGF2 Variant on the Paternal Allele in a Patient With Silver–Russell Syndrome
-н: Chun-Ling Xia, зэрэг
Хэвлэсэн: (2019-11-01)

Notiziario IGF
-н: Francesco Iacoviello
Хэвлэсэн: (2009-06-01)

Relationship of porcine <it>IGF2 </it>imprinting status to DNA methylation at the <it>H19 </it>DMD and the <it>IGF2 </it>DMRs 1 and 2
-н: Owczarek-Lipska Marta, зэрэг
Хэвлэсэн: (2011-05-01)

Correction: A novel hypomorphic allele of Spag17 causes primary ciliary dyskinesia phenotypes in mice
-н: Zakia Abdelhamed, зэрэг
Хэвлэсэн: (2021-01-01)

Expression of genes encoding IGF1, IGF2, and IGFBPs in blood of obese adolescents with insulin resistance
-н: Minchenko Dmytro O., зэрэг
Хэвлэсэн: (2019-01-01)