Maternal transmission of a humanised Igf2r allele results in an Igf2 dependent hypomorphic and non-viable growth phenotype

Maternal transmission of a humanised Igf2r allele results in an Igf2 dependent hypomorphic and non-viable growth phenotype

The cation independent mannose 6-phosphate/insulin-like growth factor 2 receptor (IGF2R) functions in the transportation and regulation of insulin-like growth factor 2 (IGF2) and mannose 6-phosphate modified proteins. The relative and specific titration of IGF2 by high affinity binding of IGF2R repr...

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Những tác giả chính:	Hughes, J, Frago, S, Bühnemann, C, Carter, E, Hassan, A
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	Public Library of Science 2013

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