Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen.

Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen.

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The response of animals to hypoxia is mediated by the hypoxia-inducible transcription factor. Human hypoxia-inducible factor is regulated by four Fe(II)- and 2-oxoglutarate-dependent oxygenases: prolyl hydroxylase domain enzymes 1-3 catalyse hydroxylation of two prolyl-residues in hypoxia-inducible...

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Dades bibliogràfiques
Autors principals:	Flashman, E, Hoffart, L, Hamed, R, Bollinger, J, Krebs, C, Schofield, C
Format:	Journal article
Idioma:	English
Publicat:	2010

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