Separate quantification of doubly and singly 13C-labeled metabolites by HSQC-filtered J spectroscopy.
NMR detection of multiply labeled compounds in biological samples is often used to follow metabolic pathways. Detection of protons bound to 13C atoms offers a more sensitive approach than direct 13C detection, but generally results in the loss of carbon-carbon coupling information. We have modified...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
1999
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