The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway.

The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway.

Protein ubiquitination and deubiquitination are dynamic processes implicated in the regulation of numerous cellular pathways. Monoubiquitination of the Fanconi anemia (FA) protein FANCD2 appears to be critical in the repair of DNA damage because many of the proteins that are mutated in FA are requir...

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Bibliographic Details
Main Authors:	Nijman, S, Huang, T, Dirac, A, Brummelkamp, T, Kerkhoven, R, D'Andrea, A, Bernards, R
Format:	Journal article
Language:	English
Published:	2005

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