The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway.

Protein ubiquitination and deubiquitination are dynamic processes implicated in the regulation of numerous cellular pathways. Monoubiquitination of the Fanconi anemia (FA) protein FANCD2 appears to be critical in the repair of DNA damage because many of the proteins that are mutated in FA are requir...

ver descrição completa

Detalhes bibliográficos
Main Authors: Nijman, S, Huang, T, Dirac, A, Brummelkamp, T, Kerkhoven, R, D'Andrea, A, Bernards, R
Formato: Journal article
Idioma:English
Publicado em: 2005

Registos relacionados