A4.9 Angiopoietin-like 4 is over-expressed in rheumatoid arthritis: a potential role in pathological bone resorption.
BACKGROUND AND OBJECTIVES: In contrast to normal synovial tissue, rheumatoid synovium is hypoxic, and expresses the hypoxia-inducible transcription factors HIF-1α and HIF-2α which allow the transcription of genes involved in angiogenesis, inflammation, apoptosis and regulation of immune function. H...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2014
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