Anti-inflammatory effects of selective glucocorticoid receptor modulators are partially dependent on up-regulation of dual specificity phosphatase 1.
BACKGROUND AND PURPOSE: It is thought that the anti-inflammatory effects of glucocorticoids (GCs) are largely due to GC receptor (GR)-mediated transrepression of NF-κB and other transcription factors, whereas side effects are caused by activation of gene expression (transactivation). Selective GR m...
Những tác giả chính: | Joanny, E, Ding, Q, Gong, L, Kong, P, Saklatvala, J, Clark, A |
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Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
2012
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