Anti-inflammatory effects of selective glucocorticoid receptor modulators are partially dependent on up-regulation of dual specificity phosphatase 1.

BACKGROUND AND PURPOSE: It is thought that the anti-inflammatory effects of glucocorticoids (GCs) are largely due to GC receptor (GR)-mediated transrepression of NF-κB and other transcription factors, whereas side effects are caused by activation of gene expression (transactivation). Selective GR m...

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Những tác giả chính: Joanny, E, Ding, Q, Gong, L, Kong, P, Saklatvala, J, Clark, A
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2012

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