Structure of the human RECQ1 helicase reveals a putative strand-separation pin.
RecQ-like helicases, which include 5 members in the human genome, are important in maintaining genome integrity. We present a crystal structure of a truncated form of the human RECQ1 protein with Mg-ADP. The truncated protein is active in DNA fork unwinding but lacks other activities of the full-len...
Príomhchruthaitheoirí: | Pike, A, Shrestha, B, Popuri, V, Burgess-Brown, N, Muzzolini, L, Costantini, S, Vindigni, A, Gileadi, O |
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Formáid: | Journal article |
Teanga: | English |
Foilsithe / Cruthaithe: |
2009
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Ábhair: |
Míreanna comhchosúla
Míreanna comhchosúla
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