Structure of the human RECQ1 helicase reveals a putative strand-separation pin.

RecQ-like helicases, which include 5 members in the human genome, are important in maintaining genome integrity. We present a crystal structure of a truncated form of the human RECQ1 protein with Mg-ADP. The truncated protein is active in DNA fork unwinding but lacks other activities of the full-len...

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Бібліографічні деталі
Автори:	Pike, A, Shrestha, B, Popuri, V, Burgess-Brown, N, Muzzolini, L, Costantini, S, Vindigni, A, Gileadi, O
Формат:	Journal article
Мова:	English
Опубліковано:	2009
Предмети:	Mutant Proteins Kinetics Protein Binding DNA Escherichia coli Sequence Alignment Adenosine Diphosphate Protein Structure, Tertiary Amino Acid Motifs Zinc Adenosine Triphosphate Conserved Sequence Amino Acid Sequence enzymology metabolism Molecular Sequence Data RecQ Helicases chemistry

Structure of the human RECQ1 helicase reveals a putative strand-separation pin. за авторством Pike, A, Shrestha, B, Popuri, V, Burgess-Brown, N, Muzzolini, L, Costantini, S, Vindigni, A, Gileadi, O

Опубліковано 2009

Journal article

Structure of the human RECQ1 helicase reveals a putative strand-separation pin.

Structure of the human RECQ1 helicase reveals a putative strand-separation pin. за авторством Pike, A, Shrestha, B, Popuri, V, Burgess-Brown, N, Muzzolini, L, Costantini, S, Vindigni, A, Gileadi, O

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