Cross−Trial Query System for Cancer Clinical Trials

Data sharing represents one of the key objectives and major challenges of today's cancer research. CancerGrid, a consortium of clinicians, cancer researchers, computational biologists and software engineers from leading UK institutions, is developing open-standards cancer informatics addressing...

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Bibliographic Details
Main Authors: Calinescu, R, Harris, S, Gibbons, J, Davies, J
Format: Book section
Published: 2007
Description
Summary:Data sharing represents one of the key objectives and major challenges of today's cancer research. CancerGrid, a consortium of clinicians, cancer researchers, computational biologists and software engineers from leading UK institutions, is developing open-standards cancer informatics addressing this challenge. The CancerGrid solution involves the representation of a widely accepted clinical trials model in controlled vocabulary and common data elements (CDEs) as the enabling factor for cancer data sharing. This paper describes a cancer data query system that supports data sharing across CancerGrid-compliant clinical trial boundaries. The formal specification of the query system allows the model-driven development of a flexible, web-based interface that cancer researchers with limited IT experience can use to identify and query common data across multiple clinical trials.