Reprogramming the immune system using antibodies.

Tolerance induction induced by monoclonal antibodies or co-receptor blockade is robust enough to resist breakdown by adoptive transfer of lymphocytes. Such resistance, the hallmark of dominant tolerance, is mediated by CD4+ regulatory T cells. CD4+CD25+ T cells inhibit lymphopenia-mediated accumulat...

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Príomhchruthaitheoirí: Graca, L, Waldmann, H
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2006

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